Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
Google Scholar citation report
Citations : 1860

Journal of Obesity & Weight Loss Therapy received 1860 citations as per Google Scholar report

Journal of Obesity & Weight Loss Therapy peer review process verified at publons
Indexed In
  • Index Copernicus
  • Google Scholar
  • Open J Gate
  • Genamics JournalSeek
  • Centre for Agriculture and Biosciences International (CABI)
  • RefSeek
  • Hamdard University
  • EBSCO A-Z
  • OCLC- WorldCat
  • SWB online catalog
  • CABI full text
  • Cab direct
  • Publons
  • Geneva Foundation for Medical Education and Research
  • Euro Pub
  • University of Bristol
  • Pubmed
  • ICMJE
Share This Page

Effects of oral and subcutaneous administration of Roselle calyx (H. sabdariffa) extract on weight management and controls

10th International Conference and Exhibition on Obesity & Weight Management

Odigie Bolaji Efosa

University of Benin, Nigeria

Posters & Accepted Abstracts: J Obes Weight Loss Ther

DOI: 10.4172/2165-7904.C1.043

Abstract
Roselle (Hibiscus sabdariffa L., family Malvaceae) is consumed in Nigeria as a refreshing drink and for therapeutic purposes. This study was to examine the effects of H. sabdariffa calyx extract on the body and organ weight of Albino rats. The second goal was to compare the effects on the target organs via routes of administration (oral against subcutaneous). Sixty Albino rats of both sexes with an average weight of 204.14�?±2.1g (Mean�?±S.E.M) were assigned by sex, age and weight to a control group (VA and VB) and test groups (IA to IVA and IB to IVB). Empirical measurements on body weight was conducted prior to and after the experiment. They were administered with varying concentrations of the extract by oral and subcutaneous routes (10 to 50 mg/kg) for 30 days at 2 days interval. On day 31, all rats were sacrificed by anaesthetization. The internal organs were excised, weighed, grossed and fixed in Bouinâ�?�?s solution for 48 hrs prior to histological processing. Sections were obtained at 3-5 microns and stained with Mayerâ�?�?s haematoxylin and eosin for light microscopy. No comparable changes are observed histologically. However, gross effects on the organs and body weight of experimental animals showed significant reduction when compared to the control (VA and VB) and test groups (IA to IVA and IB to IVB). In comparison, with the oral administration, empirical measurement showed a massive weight loss in the high dose treated animals (both routes of administration) but are marked in the oral route. Therefore, this study suggests that H. sabdariffa calyx extracts may be used for weight management and control. However, further studies are required to examine the biochemical and hematological effects in Albino rats.
Biography

Email: bolaji.odigie@uniben.edu

Relevant Topics
Top