Journal of Obesity & Weight Loss Therapy
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The prevalence of obesity and cardiovascular diseases (CVDs) is on the rise in developing countries as people tend to adopt
more urban lifestyles. Recent reports however indicate that waist and hip circumferences (WC and HC) may be better
indicators of CVD risk. The aim of the current study was to evaluate the relationship between BMI, WC and HC on blood
pressure, lipid profiles and some markers of CVD risk in female adolescents in Mthatha. 76 female high school learners, 13-
17 years old were recruited into this study: 38 were lean (BMI≤75
percentile) and 38 overweight/obese (O/O) (BMI≥85
percentile). Anthropometric and blood pressure measurements were performed for all participants, after which fasting blood
samples were collected for biochemistry. Lean learners had higher triglyceride and HDL-C while O/O learners had significantly
lower HDL-C and higher total cholesterol. Mean systolic blood pressure (MSBP) but not mean diastolic blood pressure (MDBP)
was significantly higher in the O/O group. Higher WC and HC were independently associated with significantly higher MSBP
and MDBP. Serum hs-CRP but not adiponectin levels were significantly higher in O/O group compared to the lean though
adiponectin correlated negatively with WC and HC. Increased HC and not only BMI and WC are risk factors for increased blood
pressure in female adolescents living in Mthatha.
Benedicta Nkeh-Chungag completed her Ph.D. at the age of 39 from University of the Witwatersrand, South Africa. She is an Associate Professor
of Physiology in the Walter Sisulu University. She has published 30 papers in peer reviewed journals and serves as a reviewer for several journals.
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