Journal of Obesity & Weight Loss Therapy
Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
Semen and sperm cell from hypercholesterolemic rabbits (HCR) exhibit several abnormalities such as teratospermiae, decrease
in sperm number, reduced resistance to the hyposmotic shock and spermatic dysfunction accompanying high serum
cholesterol levels and increased arterial pressure. HCR acquired these changes due to a fat diet; specifically the balanced diet for
rabbit supplemented which commercial grease from cow (approximately, 0.5% cholesterol v/v). The malformed sperm consist
in a sperm head folding in the longitudinal axes, permanent cytoplasmic droplet, and/or acrosomal swollen. Functional changes
correspond to both reduced protein tyrosine phosphorylation during sperm capacitation and percentage of acrosomal reacted
sperm under progesterone stimulation. These changes were reversed by addition of olive oil to the grease diet. We investigated
key molecules involved in cholesterol metabolism, and found changes in the expression of mRNA and protein oftranscription
proteins SREBP 1 y 2 under different diets. Clearly our results show that olive oil added to fat diet reverses the deleterious effect
of such types of diet over reproductive parameters and for the first time molecular actions of olive oil on cholesterol metabolism
Fornes Miguel Walter has completed his degree (M.D.) and Ph.D. from the School of Medicine at the National University of Cuyo (FCM, UNCuyo).
Now is the chairman of the Histology and Embryology Area from the FCM, UNCuyo and Director of basic courses at the Aconcagua University and
member of the research carrier at national research council (CONICET). He has published more than 50 papers in reputed journals devoted to the
biology of reproduction and serving as an editorial board and reviewer member of prestigious journals.
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals