alexa Olive Oil Prevents Sperm Changes Promoted By Hipercholesterolemic Diets | 14868
ISSN: 2165-7904

Journal of Obesity & Weight Loss Therapy
Open Access

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Olive oil prevents sperm changes promoted by hipercholesterolemic diets

2nd International Conference and Exhibition on Obesity & Weight Management

Fornes Miguel Walter and Saez Tania Estefania

Accepted Abstracts: J Obes Weight Loss Ther

DOI: 10.4172/2165-7904.S1.012

Abstract
Semen and sperm cell from hypercholesterolemic rabbits (HCR) exhibit several abnormalities such as teratospermiae, decrease in sperm number, reduced resistance to the hyposmotic shock and spermatic dysfunction accompanying high serum cholesterol levels and increased arterial pressure. HCR acquired these changes due to a fat diet; specifically the balanced diet for rabbit supplemented which commercial grease from cow (approximately, 0.5% cholesterol v/v). The malformed sperm consist in a sperm head folding in the longitudinal axes, permanent cytoplasmic droplet, and/or acrosomal swollen. Functional changes correspond to both reduced protein tyrosine phosphorylation during sperm capacitation and percentage of acrosomal reacted sperm under progesterone stimulation. These changes were reversed by addition of olive oil to the grease diet. We investigated key molecules involved in cholesterol metabolism, and found changes in the expression of mRNA and protein oftranscription proteins SREBP 1 y 2 under different diets. Clearly our results show that olive oil added to fat diet reverses the deleterious effect of such types of diet over reproductive parameters and for the first time molecular actions of olive oil on cholesterol metabolism is reported.
Biography
Fornes Miguel Walter has completed his degree (M.D.) and Ph.D. from the School of Medicine at the National University of Cuyo (FCM, UNCuyo). Now is the chairman of the Histology and Embryology Area from the FCM, UNCuyo and Director of basic courses at the Aconcagua University and member of the research carrier at national research council (CONICET). He has published more than 50 papers in reputed journals devoted to the biology of reproduction and serving as an editorial board and reviewer member of prestigious journals.
Top