Dersleri yüzünden oldukça stresli bir ruh haline sikiş hikayeleri bürünüp özel matematik dersinden önce rahatlayabilmek için amatör pornolar kendisini yatak odasına kapatan genç adam telefonundan porno resimleri açtığı porno filmini keyifle seyir ederek yatağını mobil porno okşar ruh dinlendirici olduğunu iddia ettikleri özel sex resim bir masaj salonunda çalışan genç masör hem sağlık hem de huzur sikiş için gelip masaj yaptıracak olan kadını gördüğünde porn nutku tutulur tüm gün boyu seksi lezbiyenleri sikiş dikizleyerek onları en savunmasız anlarında fotoğraflayan azılı erkek lavaboya geçerek fotoğraflara bakıp koca yarağını keyifle okşamaya başlar
Reach Us +44 330 818 7254


Role Of Obesity In Ischemic Stroke- Investigation Of Adipokines: Leptin, Adiponectine And Gastrointestinal Hormone Ghrelin In Stroke | 6357
ISSN: 2165-7904

Journal of Obesity & Weight Loss Therapy
Open Access

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
Google Scholar citation report
Citations : 1860

Journal of Obesity & Weight Loss Therapy received 1860 citations as per Google Scholar report

Journal of Obesity & Weight Loss Therapy peer review process verified at publons
Indexed In
  • Index Copernicus
  • Google Scholar
  • Open J Gate
  • Genamics JournalSeek
  • Centre for Agriculture and Biosciences International (CABI)
  • RefSeek
  • Hamdard University
  • OCLC- WorldCat
  • SWB online catalog
  • CABI full text
  • Cab direct
  • Publons
  • Geneva Foundation for Medical Education and Research
  • Euro Pub
  • University of Bristol
  • pubmed
Share This Page

Role of obesity in ischemic stroke- investigation of adipokines: Leptin, adiponectine and gastrointestinal hormone ghrelin in stroke

International Conference and Exhibition on Obesity & Weight Management

Ema Kantorova

Posters: J Obes Wt Loss Ther

DOI: 10.4172/2165-7904.S1.007

Introduction: Obesity, an excess of body fat, is very often associated with metabolic dysfunction of an human organism. We targeted implications of adipocytokines in ischemic stroke patients with respect to components of metabolic syndrome Methods: 145 patients (male and female) with acute ischemic stroke were enrolled for the study. The mean age of stroke patients was 66.7 ? 12.1. During the same period 68 controls, free of acute cerebrovascular disease and matched for age and sex, were recruited. The mean age of control group was 63.06 ? 11.2. Obesity measures (body mass index and waist circumference) and other components of metabolic syndrome (glycaemia, cholesterol, HDL and LDL cholesterol, triglycerides, presence of arterial hypertension) were investigated. Leptin concentrations were tested in 145 patients with ischemic stroke (80 males and 65 females) and 61 controls. Ghrelin levels were obtained from 113 stroke patients (68 males and 45 females) and 45 controls. Adiponectin levels were measured in 140 stroke patients (72 males and 68 females) and 67 controls. Results: Significantly higher levels of leptin and lower levels of adiponectin and ghrelin were confirmed in the stroke group. The level of leptin in women with stroke was three-times higher than in men, and the leptin levels positively correlated with obesity in both sexes. Positive relationship was not found between leptin, arterial hypertension and glycaemia levels in our study. Adiponectin levels were not different between men and women with acute stroke. Stroke patients in our group had hypoadiponectinemia but we did not confirm any associations with other metabolic risk factors. In our study we have found decreased levels of ghrelin in the stroke group compared to the controls but ghrelin levels didn,t correlated strongly with obesity markers. We found trend to correlation of ghrelin level and waist circumference in stroke women. Ghrelin levels correlated mildly with triglyceride levels in stroke group. Conclusions: Adipokines are supposed to play a specific role in the process of atherogenesis and in imflammatory processes generally. Bivalent activity of leptin and adiponectin is normally balanced, resulting in a healthy and steady state. Accumulation of leptin levels, started to be dangerous in situation of inadequate metabolic compensation and in impaired defensive role of adiponectin. Our results confirmed differences of leptin and adiponectin levels between the stroke and the control groups. We have found significantly higher levels of leptin and lower levels of adiponectin in stroke patients. Leptin levels correlated strongly with obesity in men and women. Ghrelin?s function in pathogenesis of stroke is not fully known. Extra-endocrine functions of ghrelin should play an important role in vascular pathology. Central effects of ghrelin are similar to cannabinoids. Ghrelin levels are high during fasting and with low BMI. Ghrelin suppresses production of proinflammatory cytokines and improves proinflammatory milieu by inhibiting T lymphocytes and monocytes. Ghrelin demonstrates potent vasodilator properties based on increased endothelial nitric oxide expression, that is endothelium and growth hormone independent.
Ema Kantorova's specialization is neurology, she finished PhD study last year (2011) and now she is a teacher, an assistant professor and postdoctoral fellow of the Jessenius Faculty of Medicine Comenius University in Martin. She studied medicine in Faculty of Medicine in Palacky University, Czech Republic. She live and work in Slovakia, Martin.