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Significance Of Exploring The Definition Of Metabolic Syndrome In Chinese Children And Adolescents | 6511
Journal of Obesity & Weight Loss Therapy
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MetS in children and adolescents are not uncommon in China. According to the national survey in 2002, the prevalence of
MetS was 2.3%, 23.4% and 35.2% respectively among normal weight, overweight and obese children. Therefore, how to
early determine and interfere with childhood MetS in China is urgent.
However, before the first universal MetS definition was launched by IDF in 2006, the studies about childhood and adolscent
MetS were all modified from adults? definition and were up to more than 40 editions. IDF MetS definition emphasizes the
central obesity and age range, mainly for ages of 10 to 16 with waist circumference percent instead of absolute waist points.
Other components such as blood lipids, blood pressure, abnormal blood glucose threshold were all refer to IDF adult definition.
Children under the age of 10 is not recommended for diagnosis of MetS, but proposed to intervene each abnormal component.
For ages of 16 years or older, adult definition was fully refered. This definition is simple and of strong operability. However, MetS
definition launched 5 years ago by IDF still has some problems: (1) single hypertension definition value without considering the
differences of children in different ages, (2) abnormal lipid cut points were not only differ from Chinese original childhood lipid
reference values, but also differ from what has recently published by American Academy of Pediatrics (American Academy of
Pediatrics, AAP) in 2011, (3) lack of abnormal component definition for children of 6 to 10 years. In addition, whether other
more simple index reflecting the child's central obesity such as waist/height ratio can be combined with? Therefore, we need to
explore and establish a suitable MetS definition.for Chinese children and adolescents
Supported by the National Key Technology R&D Program of China, and based on our previous and recent population based
study, and approved by three pediatric societies, we have set up our own MetS definition for Chinese children and adolscents.
Junfen Fu, female, born in October 1968, is the Chief Physician and Deputy Director of Endocrinology Department of Children's Hospital, Zhejiang
University School of Medicine. She is a tutor of PhD, MD. She is also the Zhejiang provincial New Century 151 Talent, the council member of the
6th Asia-Pacific Pediatric Endocrine Society, the member of Chinese Medical Association of type 1 diabetes, the committee member and secretary
of Zhejiang Pediatric Association, and the vice chairman of Zhejiang Pediatric Endocrine Society. She graduated from Zhejiang University School
of Medicine in 1991 and got her PhD degree of Zhejiang University in July of 2000. In the year of 2001, she was awarded a Chinese National
Scholarship which supported her to study in Yamagate University School of Medicine in Japan as a visiting scholar. During the year of Jul 2005 to
Aug 2006, she got a professional training in Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, University of Bristol,
UK. In the year of 2008, she got short term (3 months) clinical training in University of California, Los Angeles (UCLA). She has been working in
the Division of Endocrinology in this Hospital on clinical, teaching and research work as a pediatrician for 20 years. Her research is focused on the
prevention and treatment of obesity and diabetes in Children. She has published more than 60 papers in domestic and overseas journals within
recent 10 years. She teaches congenital metabolic disease and endocrine disease at the graduate and undergraduate levels.
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