Reach Us +44-1764-910199
Synthesis And UV Spectral Studies Of Substituted 2-(L-arabino-tetritol-1-yl) Benzimidazole Analogs: Quantitative Structure Activity Relationships (QSAR) | 36320
ISSN: 2165-7904

Journal of Obesity & Weight Loss Therapy
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Synthesis and UV spectral studies of substituted 2-(L-arabino-tetritol-1-yl) benzimidazole analogs: Quantitative structure activity relationships (QSAR)

3rd International Conference and Exhibition on Obesity & Weight Management

Mohammed A E Sallam1, Omnia G Abdel Hamid1, Sergio Abbate2 and France Lebon2

1Alexandria University, Egypt 2University of Brescia, Italy

Accepted Abstracts: J Obes Weight Loss Ther

DOI: 10.4172/2165-7904.C1.022

Benzimidazoles are compounds of wide range of biological activity. The benzimidazole nucleus in general, is an important synthetic strategy in drug discovery. Structure activity relationshipS (SAR) have indicated that there is a relationship between the inductive effect of the substituent and the biological activity of benzimidazoles. A series of substituted 2-(L-arabinotetritol- 1-yl) benzimidazole analogs with different substituents having electron attracting or electron release properties at the benzimidazole base moiety was prepared. A correlation between the inductive effect of the substituent and its spectral properties at the UV and NMR spectra were obtained. Quantitative structure activity relationship (QSAR) of the substituted benzimidazole analogs was determined. Twelve test bacteria representing three groups of bacteria were used to evaluate the biological activity of the compounds.

Mohammed A E Sallam is working as Professor of Organic Chemistry Faculty of Science, Alexandria University. He got his PhD from Alexandria University. Then he got several Postdoctral fellowships and Visiting Scientist at Biochemistry Department Purdue University, Medicinal Chemistry, Michigan State University, Medicinal Chemistry, Ohio State University, Department of Chemistry, University of Trondheim, Norway. He is Board editor at several Journals; J. of Carbohydrate Chemistry, 1983-2000, Green and sustainable Chemistry, GSC, 2011-prewsent, and Vitamins and Minerals Reports, November 2013- present His Major field is Carbohydrates and C-nucleosides.

Email: [email protected]

Relevant Topics