Seiichi Osako | OMICS International
ISSN: 2167-0846

Journal of Pain & Relief
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Seiichi Osako


The Role of GABAA Receptor δ Subunit and its Agonist THIP in Thermal Hypersensitivity in a Mouse Model of Neuropathic Pain

Decreased gamma-aminobutyric acid (GABA)-mediated phasic inhibitory transmission in the spinal cord is thought to be responsible for the development of neuropathic pain. However, the role of GABAergic tonic current in substantia gelatinosa (SG) neurons remains to be fully elucidated. Using real-time polymerase chain reaction, we investigated the ex... Read More»

Saya Hakata, Ayako Takahashi, Akira Iura, Seiichi Osako, Hironobu Uematsu, Yoichi Matsuda and Yuji Fujino

Research Article: J Pain Relief 2018, 7:308

DOI: 10.4172/2167-0846.1000308

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article