Clean and Efficient One-Pot Synthesis of New 2-Oxo-2,3-Dihydro-1H-Pyrrole-3-Carboxylic Acid and 2-Oxo-1,2-Dihydro-Pyridine-3-Carboxylic Acid Derivatives through Ball Milling under Catalyst-Free and Solvent-Free ConditionsMohamed Ould M’hamed*
Department of Chemistry, College of Sciences, Al Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
- *Corresponding Author:
- Mohamed Ould M’hamed
Department of Chemistry, College of Sciences
Al Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia
E-mail: [email protected]
Received date: 10/11/2015; Accepted date: 17/11/2015; Published date: 20/11/2015
A high-yielding one-pot ball milling method for the synthesis of new 2-oxo-2,3-dihydro-1H-pyrrole-3-carboxylic acid and 2-oxo-1,2-dihydropyridine- 3-carboxylic acid was developed under solvent-free and catalyst free conditions. The proposed method is simple and has environmental and economic advantages.