alexa IN SILICO PREDICTIONS FOR MANIPULATIONS OF TESTIS SPECIFIC HEAT SHOCK PROTEIN HSP-70 GENES -HSPA2 AND HSPA1L WITH CALOTROPIS LATEX IN REGULATING MALE FERTILITY | Abstract


Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access

Abstract

Regulation of male fertility is needed to protect the health of the society. It is well proved that Heat Shock Proteins (HSPs) influence various aspects of reproduction wherein the expression of HSP 70 is an essential part of sperm development. We reported the spermicidal effect of the latex of the medicinal plant Calotropis. In our effort to design dual action spermicide from Calotropis, in this study, different bioinformatics tools were used to find the possible manipulations of testis specific HSP genes-HSPA2 and HSPA1L with Calotropis sp. Besides the results of Ligand-Protein docking with Arguslab software, the predictions carried out online with STRING and STITCH databases along with GNCPro Gene Central Network and Array Express would be useful in custom designing of high throughput array experiments to have guided metabolite gene network in regulating male fertility with Calotropis- HSP

To read the full article Peer-reviewed Article PDF image

Author(s): R.G.Hemalatha and Dr.E. Padmini

Keywords

HSP-Heat shock proteins, HSF-Heat Shock Factor, Calotropis latex, Ligand Protein Docking, Gene interactions, Microarray expression, Protein Suppliments

Recommended Journals

Share This Page

Additional Info

Loading
Loading Please wait..
 
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords