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Research Article Open Access
The present studies designed as In vitro antimicrobial activity of the whole plant of Cardiospermum halicacabum Linn. The traditional Indian system of medicine has a very long term history of usage in a number of diseases and disorders, but lacks recorded safety and efficacy data. However the main cause for their scientific neglect is multi constituent mainstay and the mechanism of action being unclear. Development of standardized, safe and effective herbal formulations with proven scientific evidence can also provide an economical alternative in several disease areas. Herbs have been used as a source of drugs to combat diseases since time immemorial. The effectiveness, easy availability, low cost and non-toxic nature popularized herbal remedies. In spite of the dramatic development of synthetic drugs and antibiotics as the major therapeutic agents, herbs continue to provide basic raw material for some of the most important drugs. Its roots are used for medicinal purposes. In this study Methanol and acetone leaf & root extract of Cardiospermum halicacabum Linn were investigated for in vitro antibacterial property by agar disc diffusion method. The crude extract of Cardiospermum halicacabum Linn, the acetone and Methanol root extract showed good antimicrobial activity against the Salmonella typhi & Proteus mirabilis. Leaf extract of ethanol showed good antimicrobial activity against the Proteus mirabilis. Leaf extract of acetone showed moderate inhibition activity against the Staphylococcus aureus.
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Author(s): V. Krishna Murthy Naik, K. Sudhakar Babu, J. Latha, M. Swarna Kumari