alexa Abstract | Microwave assisted synthesis of 3-(Tetrahydro- 3,4,5-trihydroxy-6-hydroxymethyl-2H-pyran-2- yloxy)-2-aryl/heteroaryl-4H-chromones and their biological importance
ISSN ONLINE(2319-8753)PRINT(2347-6710)

International Journal of Innovative Research in Science, Engineering and Technology
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This research communication is toward the investigation of microwave synthesis and biological evaluation of 3-(tetrahydro-3,4,5-trihydroxy-6-hydroxymethyl-2H-pyran-2-yloxy)-2-aryl/heteroaryl-4H-chromones (3-O-􀈕-Dglucopyranosyloxyflavones). These compounds have been obtained by the interaction of α-acetobromoglucose with 3- hydroxy-2-aryl/heteroaryl-4H-chromones under microwave condition. The structures of these newly synthesized 3-O- 􀈕-D-glucopyranosides were established on the basis of chemical, elemental, and spectral analyses. Further, All compounds were evaluated for antimicrobial activity. The inhibition caused by 3-hydroxy flavones was relatively low whereas that of its 3-O-􀈕-D-glucopyranosides analogues was substantially more

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Author(s): Mangesh Gharpure, Vishwas Ingle, Harjeet Juneja, Ratiram Choudhary and Nilesh Gandhare

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