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Review Article Open Access
From the last decade Mouth dissolving tablets are gaining more prominence as a novel drug delivery system & emerges as one of the popular & widely accepted dosage forms, especially for pediatric patients because of incomplete development of muscular & nervous system & in case of geriatric patients suffering from Parkinson’s disorder or hand tremors, from both pharmaceutical industries as well as patients because they are convenient to be manufactured & administered, free of side effects, offering immediate release & enhance bioavailability , so as to achieve better patient compliance. MDT is a good choice of drug delivery for pediatric & geriatric patients because it troubleshoots the problem of dysphagia i.e. difficulty in swallowing which is seen in many elderly patients. Mouth dissolving tablets offers rapid disintegration so as it dissolves very fast in saliva & then easily swallowed without the need of water which is a major benefit over conventional dosage form. The popularity and usefulness of the formulation resulted in development of several mouth dissolving tablet technologies for preparation. The current article is focused on ideal characteristics, advantages and disadvantages, formulation aspects, formulation technologies, evaluation of products and future potential. Various marketed preparations along with numerous scientific advancements made so far in this avenue have also been discussed.
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Author(s): Erande Kumar, Joshi Bhagyashree