alexa Abstract | Study to Evaluate the Effects of Periodontitis and Type II Diabetes on Serum and Salivary Superoxide Dismutase Levels
e-ISSN: 2320-7949 and p-ISSN: 2322-0090

Research & Reviews: Journal of Dental Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access

Abstract

Objectives: 1. Estimation of SOD levels in saliva and serum of a) Healthy patients b) Patients with chronic periodontitis c) Patients with type-II diabetes mellitus & d) Patients with type-II diabetes mellitus along with chronic periodontitis. 2. To evaluate changes in SOD levels in saliva and serum after SRP in above four mentioned groups.

Materials and Methods: This study was carried out on 40 subjects selected by random sampling method from the Outpatient Department of Periodontology, B.V.D.U Dental College and Hospital, Navi Mumbai. Study was approved by the institutional ethical committee. The selected subjects were divided into 4 groups as, Group I: Control group of ten Patients, Group II: Ten Patients with chronic periodontitis and diabetes mellitus (type II), Group III: Ten patients with chronic periodontitis and Group IV: Ten Periodontally healthy patients with diabetes mellitus (type II). Periodontal parameters, i.e. plaque index, gingival index, probing pocket depth and clinical attachment level were assessed at baseline. Blood and saliva samples were collected at baseline and on 10th day after SRP. SOD levels were estimated by using ELISA kit. Statistical analysis was done by ANOVA test.

Results: SOD concentration was higher in Group II compared to other groups. After non surgical therapy there was significant decrease in SOD concentration in all groups. (P<0.05)

Conclusion: This study shows an additive effect of diabetes and chronic periodontitis on the oxidative stress. It can be concluded that SRP is helpful to decrease the oxidative stress in periodontitis and diabetes.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Dr. Varsha Rathod, Dr. Sainath Salunkhe,  Dr. Nilesh V. Joshi

Keywords

Periodontitis, Diabetes, Oxidative Stress, Saliva, Serum, SOD-Superoxide Dismutase, SRP- Scaling and Root Planning , Periodontitis, Diabetes

Share This Page

Additional Info

Loading
Loading Please wait..
 
 
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords