Dr. Richard D. Smith is Chief Scientist in the Biological Sciences Division and Director of Proteomics Research at Pacific Northwest National Laboratory (PNNL). Dr. Smith is Director of the NIH Biomedical Technology Resource Center for Integrative Biology and the U.S. DOE High Throughput Proteomics Facility at PNNL. He is the author or co-author of more than 750 publications. Dr. Smith holds thirty-seven patents and has been the recipient of nine R&D 100 Awards, the 2003 ACS Award for Analytical Chemistry, and the 2009 HUPO Discovery Award in Proteomics Science

Development and application of methods and instrumentation for biological applications. Development of the first combinations of capillary supercritical fluid chromatography and capillary electrophoresis with mass spectrometry. Development and application of capabilities for making ultra-sensitive and high performance proteomics and metabolomics measurements.

The MPC is a key player in developing of proteomics technologies and approaches. The research focus is on the protein analytical study of biological systems with the help of multidimensional separation methods and the biological mass spectrometry (MS).Especially by using innovative strategies of quantitative protein analysis, new insights in the development of diseases will be gained as well as detailed information about localization, function and interaction of proteins. The MPC can offer an excellent infrastructure with all necessary state-of-the-art technologies (2D gel electrophoresis, DIGE, multidimensional/nanoHPLC, ESI-ITMS, MALDI-TOF/TOF, ESI/MALDI-QTOF etc.) and an excellent bioinformatics structures.

Proteomics,Structural determination

Dr. Srivastava is Chief of the Cancer Biomarkers Research Group in the Division ofCancer Prevention, National Cancer Institute. Dr. Srivastava received his PhD. Degree inbiological science from Banaras Hindu University in 1977. Subsequently, he received hisM.S. degree in Computer Science from the Virginia Commonwealth University in 1987and a MPH degree from the Johns Hopkins University in 1997. He did postdoctoral workat the University Of Osaka, Japan; the University of California at San Francisco; and theUniversity of Arizona, Tucson. He joined the National Cancer Institute in 1988. Since1990, he has served as program director in the Division of Cancer Prevention and focusedhis responsibility in developing and managing programs in molecular diagnostics withprimary emphasis on cancer screening, early detection, risk assessment and informatics.Dr. Srivastava has received several honors and awards and is a member of a number ofscientific committees. In 1995, he was elected to the American Joint Committee onCancer (AJCC) which is responsible for developing staging criteria for cancers forworldwide use and currently serves on the AJCC Executive Committee. He has receivedseveral NIH Merit Awards. In 1999, he also received the NIH Director’s Award for hisextraordinary scientific leadership in furthering deve lopment of biomarkers and surrogateendpoint in clinical trials. He conceptualized and initiated a Gordon Conference on NewFrontiers in Cancer detection and Diagnosis (2002) and chaired and coordinated themeeting in 2003.

Cancer Biomarkers,Biomechanical Changes,Public health

Fuchu He, PhD, Member of the Chinese Academy of Sciences, Member of
the Academy of Sciences for the Developing World, is currently the Director and Professor of State Key Laboratory of Proteomics, Beijing Proteome
Research Center and Beijing Institute of Radiation Medicine; council member of Human Proteome Organization (HUPO); co-chair (inaugural chair) of HUPO Human Liver Proteome Project (HLPP), the vice-president of AOHUPO, the president of CNHUPO. He received his B.S. degree in Genetics from Fudan University, Shanghai in 1982. Then he earned his M.S degree in Biochemistry and Ph.D. in Cell Biology from Beijing Institute of Radiation Medicine. As corresponding author, he has published more than 160 papers in international peer-reviewed journals, including Nature Cell Biology, Nature Genetics, Nature Biotechnology, Nature Methods, Nature Protocol, Science, PNAS, EMBO J, Gastroenterology, Hepatology, Genome Res, Mol Cell Proteomics, Cancer Res, J Proteome Res, JBC, Human Mutation, Oncogene, Proteomics, Bioinformatics, etc.

His major fields of research are proteomics, genomics, bioinformatics and
systems biology, especially for liver physiology and pathology.

Sandra Orchard coordinates the annotation and production of the IntAct molecular interaction database (www.ebi.ac.uk/intact) at the European Bioinformatics Institute. She also manages the IMEx consortium of collaborating interaction databases. She is a Steering Committee member of the HUPO Proteomics Standards Initiative and in particular of the Molecular Interaction workgroup. She is also a member of the Publication and Education committees of HUPO.

Protein annotation
Molecular interactions
Network analysis

Osmania University, Hyderabad, India B Sc 1969 Chemistry-  Bsc Osmania Univeristy, Hyderabad, India M Sc 1973 BioChemistry-MscOsmania University, Hyderabad, India Ph D 1980 BioChemistry-PhdWashington University Medical School, St Louis, MO,-PDFUSA PDF 1982-87 Bio chemistry, Mol Biology

Chemistry,Biochemistry,Mol Biology

Cathy H. Wu is the Director for Center for Bioinformatics &  Computational Biology, Professor, for Computer & Information Sciences and Biological Sciences, University of Delaware, Adjunct Professor, Biochemistry
and Molecular & Cellular Biology, Georgetown University Director, Protein Information Resource (PIR). Dr.Wu received Ph.D. in 1984 from Purdue University. She has conducted bioinformatics research for 20 years, led the PIR as a major bioinformatics resource to support genomics, proteomics and systems biology research, and served as PI/Co-PI on large consortium projects, including UniProt. She serves on the advisory committees for the NIGMS Protein Structure Initiative, NSF TeraGrid, NRC Board on Research Data and Information, US HUPO, and Protein Data Bank. She has served on over 40 program committees for international conferences, published about 150 peer-reviewed papers and three books, and given more than 110 invited
lectures.

Protein Structure-Function-Evolution
Proteomic
Bioinformatics
Biomedical Text Mining
Biomedical Ontology
Omics Data Integration
Computational Systems Biology
Bioinformatics
Cyberinfrastructure

He is interested in the discovery of biomarkers and therapeutic targets for HCV-related Hepatocellular Carcinoma and Pancreatic Cancer using two-dimensional gel electrophoresis combined with tandem mass spectrometry, and in the development of Cys-tag-Protein Chips for high through-put analyses of protein-protein interactions. His interest is shifting to Membrane Proteomics, Cancer Immunology and Immuno-Proteomics for the development of new diagnostic tools and non-invasive curative treatments of malignant tumors. He is also serving for the promotion of proteomics as an Associate Editor of Proteome Science, and an Editorial Board Member of Proteomics, Expert Review of Proteomics, and so on. His mission is to promote E&T of graduate students and young scientists being experts in the field of functional proteomics and clinical proteomics for understanding Molecular System of Life.

Professor Richard Simpson received his PhD in biochemistry and chemistry at Melbourne University, Australia in 1974. After post-doctoral studies at the NIH, Bethesda, Maryland, he returned to Australia as a Research Fellow at St. Vincent·s Institute of Medical Research, Melbourne. He is currently the Head of the Joint Protoemics Laboratory of the Ludwig Institute for Cancer Research and the Walter and Eliza Hall Institute of Medical Research, a Research Professor at the University of Melbourne and Adjunct Professor at Yonsei University, Korea. He is the Chairperson of the Human Proteome Organization (HUPO) Finance Committee and Treasurer of HUPO. On a national level, Professor Simpson is the President of the Australasian Proteomics Society (APS). Professor Simpson was awarded, in 2003, the Centenary Medal from the Australian Government “For service to Australian society in research and development” and in 2008 received the HUPO Distinguished Service Award “For indispensible contributions in his service to HUPO since the inauguration of HUPO in 2000”. He has published over 352 research publications, has an h-index of 60 (based on ISI citations as of August 16, 2007). [ref. J.E. Hirsch, Proc. Nat. Acad. Sci. 2005, 102, 16569] and holds 14 patents. With the Cold Spring Harbor Laboratory Press, Professor Simpson has written three leading text books on proteomics – Proteins and Proteomics: A Laboratory Manual (2003), Purifying Proteins for Proteomics: A Laboratory Manual (2004) and, more recently Basic Methods in Protein Purification and Analysis: A Laboratory Manual (2009).

Proteomics, Structural determination

Terence C.W. Poon is currently Associate Professor at the Department of Paediatrics, the Chinese University of Hong Kong. Dr. Poon received his B.Sc. degree in Biochemistry, Ph.D. degree in Pathological Sciences and postdoctoral training from the Chinese University of Hong Kong. Later he received a M.Sc. degree in Bioinformatics from the University of Manchester. Dr. Poon has a major interest in development of proteomic and bioinformatic methodologies and their applications to gastrointestinal disease research, especially on diagnosis and clinical outcome prediction. His research team is identifying the cellular proteins differentially expressed in liver cancer. Recently he has joined the China Human Proteome Organization, and participates in the Chinese Human Liver Proteome Project. Currently he is the Council member of the Hong Kong Proteomics Society, and the Vice President of Hong Kong Society of Mass Spectrometry. In 2007, he received the Most Promising Young Researcher Award from the Food and Health Bureau of the Hong Kong SAR Government.

Biochemistry, Pathological Study, Clinical Oncology

Laura Beretta’ studies went on University of Paris VI, France B.S. 1983 Cellular BiologyUniversity of Paris VI, France M.S. 1984 Cellular BiologyUniversity of Paris VI, France Ph.D. 1989Molecular and CellularPharmacology

Hepatitis C virus (HCV) infection affects 3% of the world population (2% of the US population). HCV persists in the large majority of infected patients. We are using a combination of proteomics and gene silencing technologies to identify cellular proteins involved in HCV replication in hepatocytes. We are also studying HCV-related hepatocellular carcinoma (HCC). The incidence of HCV-associated HCC is rising in the United States and is likely to triple over the next 10 to 20 years. This new trend is largely due to the high prevalence of HCV infection in the population. The overall survival rate of HCC is poor because most patients are diagnosed when the tumor is in an advanced stage. Our group has embarked on a major effort to integrate transcriptomics and proteomics for identifying new markers for early diagnosis of HCC and for identifying defective signaling pathways and their signature in hepatocytic transformation. We are also using mouse models of HCC to identify molecular events associated with hepatocarcinogenesis.

Dr. Zhengping Yi is an Assistant Research Professor in the Center for Metabolic & Vascular Biology and the School of Life Sciences at ASU and directs the Proteomics Laboratory.  Dr. Yi completed his Ph.D in Chemistry at Nanjing University, P. R. China in 2000 and did post-doctoral work in Biochemistry at Purdue University and post-doctoral work in proteomics and diabetes at the University of Texas Health Science Center at San Antonio. His current research funded by NIH and ADA focuses on insulin signaling and its associated problems with insulin resistance and type 2 diabetes.

Dr. Yi’s research focuses on a better understanding of the basic biology of insulin signaling and the etiology of insulin resistance, type 2 diabetes (T2D), as well as their complications.  Dr. Yi and his group are using a combination of clinical, biological, and proteomic approaches to better comprehend insulin signaling and the associated problems that occur with obesity and T2D.  Studying insulin signaling in humans is challenging.  Dr. Yi’s laboratory has developed state-of-the-art techniques that can be used to better define and understand the effect of insulin in key metabolic tissues in humans such as skeletal muscle.  These approaches are useful models for studying cell signaling pathways in general, and especially their regulation by protein phosphorylation and protein-protein interactions. In addition to directing his independent laboratory working on insulin signaling both in vitro and in vivo, Dr. Yi also directs the Proteomics Laboratory in the Center for Metabolic and Vascular Research.  The Proteomics Laboratory is well equipped with two 2D-HPLC-ESI-MS/MS systems, including one Thermo LTQ-FT-Ultra.  It is one of the most sensitive instruments with high mass resolution and mass accuracy available for complex proteomic studies. Proteomics offers the capability to simultaneously quantify multiple proteins, protein-protein interactions, and protein phosphorylation, providing a better picture of complex protein networks.

Ho Jeong Kwon belongs to the Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University

Chemical Genomics

Christian Stephan is Head of Bioinformatics,Medizinisches Proteome-Center (MPC),Ruhr-Universität Bochum

Computational Proteomics, Genomics

October 12, 1950, but officially its February 18, 1951 in southern Taiwans Tainan County, in the rural town of Guantian. Supposedly, Chen was born months before his parents registered his birth because he was sickly and they werent sure he would survive - hence the differing birth dates.

Proteomics and Computational Proteomics

Young Mok Park is a Graduate School of Analytical Science and Technology, Korea Basic Science Institute.

Mass spectrometry, Molecular Biomarkers

Ruth vanbogelen belongs to Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48109-0606, and Pfizer Global Research and Development.

molecular biomarkers, proteomics

Babu Purkayastha is a member of Senior Director R&D Proteomics Research Centre Applied BiosystemsFramingham, MA, USA

Proteomics, Analytical techniques in proteins

Roman Zubarev education was in Drexel University, Philadelphia, PA, September 2004 - June 2009

Mass spectrometry, Molecular Biomarkers

Lennart Martens is Professor of Systems Biology in the Department of Biochemistry at the Medical Faculty of Ghent University in Ghent, Belgium. He is also Group Leader of the Computational Omics and Systems Biology Group of the Department of Medical Protein Research at VIB in Ghent, Belgium. He obtained his Ph.D. in Sciences: Biotechnology from Ghent University, Belgium in 2002-2006. Prof. Martens serves in the editorial boards of several journals in the field, is a frequent speaker at international conferences, and has published over 70 peer reviewed papers over the past five years.

Bioinformatics
Computational biology
Systems biology
Proteomics
Genomics
Transcriptomics

David Fenyo education was in Uppsala University, Sweden M.Sc. 1987 Engineering PhysicsUppsala University, Sweden Ph.D. 1991 PhysicsThe Rockefeller University, New York, NY Postdoc 1992-1997

Proteomics Engineering, Biophysical studies

Wangs Alliance project extends to tumor glycomics with a current focus in exploration of glycan markers of prostate cancers and anti-glycan autoantibody signatures in prostate cancer patients. This is in partnership with Co-Investigator Ten Feizi at Imperial College London, UK. The Feizi group pioneered carbohydrate ligand discovery; the unique neoglycolipid technology coupled with mass spectrometry established by them was the basis of an advanced microarray system encompassing sequence-defined carbohydrate chains of glycoproteins and glycolipids. Among outputs are assignments of ligands for numerous endogenous carbohydrate recognition systems and those in pathogen host interactions including the oncogenic simian virus 40, SV40 and the pandemic H1N1 2009 influenza A virus.

Wangs long-term research interest is in the immunogenic sugar moieties that play key roles in the host recognition of complex carbohydrates and immune responses to carbohydrate antigens.

Mario Hugo Genero, MD is a Cofounder and Scientific Director of BMG BioPharma. He has received a MD degree from Buenos Aires University, Buenos Aires, Argentina. (1990) Adjunct Professor of Medical Genetics, Austral University (2005-2009). He has served as Council Member of The Human Proteome Project (HUPO) for two period (2003-2009). He is serving as coordinator of the Latin America HUPO. He is participating in the Cardiovascular Initiative at HUPO. He also is serving at the Education and Training Committee of The Human Proteome Project (HUPO) as coordinator of specific educational needs of "Proteomics less advanced Countries

Bioinformatics.
Biologicals, biosimilars, biobetters, PEGylated-Biotherapeutics.
Mass spectrometry, MALDI-TOF, Imaging MS, nHPLC-Ms-MS, Glycomics, Immunomics, ICP-Ms, nHPLC-QQQ, Real Time PCR, STR, Sorter Flow Citometry Aptamers.
HLA-based vaccines, H5N1, H1N1.
Biobanking.
Human Induced Pluripotent Stem Cells

Phan Van Chi is a Head, Protein Biochemistry Lab and Proteomics Unit in Institute of Biotechnology (IBT) Vietnam Academy of Science & Technology (VAST)

Genomic, Proteomic, Bioinformatic, Gene technology, biotechnology in microorganisms

Mikhail Kirpichnikov is a Full Member of the Russian Academy of Sciences, Dean, Faculty of Biology, Moscow State University, Moscow, Russia

Proteomics, Analytical techniques in proteins

Hrishikesh Chakraborty has more than 20 years of collaborative research experience and expertise in mathematical modeling, public health, medical, epidemiology, and social science research. He has a tract record of obtaining external funding. He designs surveys, single- and multisite randomized clinical trials and cluster randomized clinical studies, including stratification and randomization plans, sample sizes, and analysis plans. He directs and conducts data analyses to support design decisions, interim reporting requirements, and publication of final results. Dr. Chakraborty has served in key coordinating center roles as principal investigator, co-principal investigator, task leader, and senior statistician for large multicenter clinical and social studies. He has been providing statistical consultation for more than 15 years and has accumulated experience in both academic and private research environments. He also has experience in phase II/III/IV-drug development studies and submissions to the U.S. Food and Drug Administration (FDA) for IND/NDA in different areas. His statistical expertise includes mathematical modeling, longitudinal data analysis, hierarchical linear models, multivariate general linear models; mixed models include hierarchical modeling, categorical data analysis methods, propensity score modeling, survival analysis, simple and clustered randomized trial design and analysis, non-parametric methods, survey methodology, and simulations studies. He also has excellent knowledge of and experience in data management, project management, statistical computing, quality assurance/quality control, and clinical and observational data analysis. Dr. Chakraborty has published widely on a variety of topics in scientific and statistical journals and presents his research at scientific meetings as a contributing and invited speaker. He regularly reviews journal articles as an external reviewer for different journals and also reviews grant proposals for National Institute of Health (NIH) and the Department of Education as an expert reviewer or special emphasis panel member

Mathematical modeling, public health, medical, epidemiology, and social science research

Lifeng Peng and K Shimizu. 2005. Effect of fadR gene knockout on the metabolism of Escherichia coli based on analyses of protein expressions, enzyme activities and intracellular metabolite concentrations. Enzyme and Microbial Technology 38:512-520.Lifeng Peng , Marcos J. Arauzo-Bravo, Kazuyuki Shimizu. 2004. Metabolic flux analysis for a ppc mutant Escherichia coli based on 13C-labelling experiments together with enzyme activity assays and intracellular metabolite measurements. FEMS Microbiology Letters, 235(1):17-23.Lifeng Peng , Kazuyuki Shimizu. 2003. Global metabolic regulation analysis for Escherichia coli K12 based on protein expression by 2-dimensional electrophoresis and enzyme activity measurement. Applied Microbiology and Biotechnology, 61(2):163-178

My research interests are concerned with cellular metabolism and metabolic engineering. Approaches include transcript, proteome, metabolite and metabolic flux analysis using RT-PCR, 2D electrophoresis, HPLC/GC mass spectrometry and 13C-NMR.

Dr. Choi is a biostatistician with primary interest in statistical modeling of various data in medicine and biology. In addition, he has interests in statistical genomics/proteomics, ophthalmology, environmental health problems and researches in spatial-temporal models.

Statistical genomics/proteomics, ophthalmology, environmental health problems and researches in spatial-temporal models.

Rong Luo is a Doctor of Philosophy in Mathematics, West Virginia University, 2002 (Advisor: Cun- Quan Zhang) Master of Science in Computer Science, West Virginia University, 2002 (Advisor: Elain Eschen) Master of Science in Mathematics, University of Science and Technology of China, 1998 (Advisor: Jiongsheng Li) Bachelor of Science in Mathematics, University of Science and Technology of China, 1996

Graph Theory, Combinatorics, Combinatorial Matrix Theory,Mathematical Chemistry

Peter Nilsson is an Associate Professor of Biotechnology at the Department of Proteomics at KTH - Royal Institute of Technology, Stockholm, Sweden. He took his Ph.D. degree in Biotechnology at KTH in 1998. He has been the Head of the KTH Microarray Center between 1999 and 2008, with massive production and analysis of various types of DNA microarrays within the KTH Genome Center. He has since 2002 also been heading the protein array activities within the Human Protein Atlas project (www.proteinatlas.org). The main focus is on the development and utilization of array-based technologies for validation of antibodies and for systematic antigen- and antibody-based plasma profiling. He has been a member of HUPO since 2003.

Proteomics, Microarrays, Biotechnology

Bas van Breukelen graduated at the Wageningen Agricultural University on Bioprocess Engineering with specialization molecular biology and biochemistry. He received his PhD at the Utrecht Medical Centre in 2003 on the subject of the Adenovirus DNA replication and Recombination. After his PhD he made a career switch to the field of Bioinformatics. His first experience in the field of bioinformatics was at the department of biology working on the bioinformatics for the Complete Arabidopsis Thaliana MicroArray and the CBSG. There he was involved in statistical analysis of microarrays as well as setting up a LIMS and Pipeline for the analysis of these microarrays.

Bioinformatics, Proteomics, Bioanalysis

Dr. Conrads is co-director of the Clinical Proteomics Facility at the University of Pittsburgh Cancer Institute and associate professor of pharmacology, biomedical informatics and medicine in the University of Pittsburgh School of Medicine. An expert in the development of new biomarkers to detect cancer early, Dr. Conrads has an extensive background in proteomics and metabolomics. His research also aims to develop and use novel technologies that bridge the fields of chemistry and biology. In practice, his research relies on the application of a technique called mass spectrometry to separate and analyze proteins.

Chemotherapy, Biomarkers

Hua Xu is a research assistant professor of Research Resources Center, University of Illinois at Chicago, and Department of Medical Chemistry & Pharmacognosy, University of Illinois at Chicago, Chicago, IL. He has received a PhD in Chemistry at The Ohio State University, Columbus, OH in 2003-2007. He has received a M.S. in Chemistry at Nanjing University, Nanjing, Jiangsu, China in 2000-2003. He has completed his B.S. in Chemistry at Nanjing University in 1996-2000. He has published 21 research papers on peer-reviewed scientific journals including Bioinformatics, BMC Bioinformatics, Journal of Proteome Research, Proteomics, Journal of the American Society for Mass Spectrometry, and Journal of Physical Chemistry B. He has also reviewed manuscripts for Journal of Proteome Research, Molecular & Cellular Proteomics, Bioinformatics, Analytical Chemistry, and Computational Biology and Chemistry.

Bioinformatics for Proteomics
Mass Spectrometry-Based Proteomics

Viola Calabrò is Associate Professor of Genetics at the University of Naples, “Federico II”. Faculty of Biotechonological Sciences. She is a member of the teaching staff for the PhD School of Biotechnology and member of the executive board of the “AGI” (Italian Association of Genetics). She is member of the Competence for “Oncogenomics”, University of Naples, Naples, Italy (2003-2010). She is member of the Academic College for the PhD students in Biotechnological Sciences. Reviewer for the “Cancer Research UK” projects (2004).

Staff Scientist and Head of the Laboratory of Molecular Genetics at the Dept. of Structural and Functional Biology of the University of Naples “Federico II”, she works on the Structural and Functional characterization of genes controlling cell proliferation, differentiation and tumorigenesis such as the p14ARF tumor suppressor and p63.

Gerardo Nava belongs to Washington University School of Medicine Department of Pathology & Immunology

Proteomics Engineering, Biophysical studies

Xiang-Jia Min is Assistant Professor in the Center for Applied Chemical Biology, Youngstown State University.  He received his Master degree in Software Systems from University of British Columbia in 2002 and his PhD in Plant Science from University of Hawaii in 1995. He is serving on the Ohio Plant Biotechnology Consortium as the YSU representative.  He is an editorial board member of the Journal of Proteomics and Bioinformatics and a reviewer for the following journals:  Bioinformatics; Journal of Proteimics & Bioinformatics ; Nucleic Acids Research; Molecular Biology and Evolution;  Folia Microbiologica.  He has published 25 papers in journals and books.  He implemented some widely used software tools including OrfPredictor, TarngetIdentifier and ASFinder.

Bioinformatics software and database development - software tools for DNA seqeunce analysis, ORF prediction, identification of alternatively spliced genes, and data mining; knowledge database development for secretomes; Gene and genome annotation and evolutionary analysis.

Qiangwei Xia has received a PhD in Molecular and Cellular Biology from the University of Washington in 2007. Due to his significant impact on the field of quantitative proteomics, Dr. Xia received the 2006 China National Award, the Chinese government’s highest level postgraduate education award. Throughout an impressive nine (9) year research career, Dr. Xia has been working in the field of mass spectrometry-based proteomics. He has made distinct contributions in mass spectrometry instrumentation, bioinformatics, microbial biology research, human oral pathogen research, cancer research, neurodegenerative disease research, biomarker discovery, and stem cell research. Dr. Xia is the author of eighteen (18) peer-reviewed articles. Dr. Xia serves as a reviewer for Analytical Chemistry, Journal of Proteomics, and BioTechniques. In his upcoming position at Regeneron Pharmaceuticals, Dr. Xia will be leading studies performed in the Analytical Biochemistry Group to characterize therapeutic proteins using cutting-edge mass spectrometry techniques.

Quantitative Proteomics
Protein De novo Sequencing
Protein Post-translational and In-process Modifications
Mass Spectrometry Instrumentation
Bioinformatics Software Development
Peptide Fragmentation Technology
Protein/Peptide Biomarker Discovery
Protein Structural Characterization.

Dr. Chitti babu Education went on in  University of California at San Diego San Diego Supercomputer Center Post-Doctoral Research Associate, Structural Bioinformatics 1997-1999 Iowa State University at Ames Department of Genetics, Developmental & Cell Biology Post-doctoral Research Associate, Molecular BiologyIowa State University at Ames Department of Computer Science Non-degree student, Computational Biology Auburn University at AuburnDepartment of Biological Sciences Ph.D., Thesis Title: Expression of foreign genes in plant chloroplasts  College of Agriculture (ANGRAU), Rajendranagar, India Department of Genetics and Plant Breeding M.Sc.(ag), Seed Science and Technology Agricultural College, (ANGRAU), Bapatla, India. B.Sc.(ag), Agricultural Sciences

Comparative analysis of cancer protein interaction networks Inferring domain-domain interactions from protein-protein interactions Cataloguing the organellar proteomes of eukaryotes

Song Cao is a research associate in the department of physics at the University of Missouri. He has received a Ph.D. from Zhejiang University, China, 1999-2003. He is serving as the reviewer for several Journals, such as Physical Review Letters, Physical Review E, Bioinformatics, Bioinformatics and Biology Insights, Biomedical Engineering and Computational Biology et al.

Computational studies on cellular events including pre-mRNA splicing, telomerase activity and ribosomal frameshifting.
Secondary structure predictions of RNA pseudoknots and RNA/RNA complexes.
Thermodynamics and kinetics of RNA folding.
Mechanical unfolding of RNA molecule.
De novo prediction of RNA 3D structure.
Computational studies of complex adsorption systems.

Lalit Ponnala is a research associate of the Biotechnology Institute at Cornell University. He is affiliated with the Cornell Life Sciences Core Laboratories Center and the Center for Advanced Computing. He received a PhD in computational biology from North Carolina State University, Raleigh, NC in February 2007. He has over 15 publications in international journals and conference-proceedings, and has served as a reviewer for 7 prominent journals.

High-throughput transcriptomics
Quantitative proteomics
Biomolecular structure
Comparative genomics
Genetic diversity and polymorphism

Identify splicing regulatory cis-elements and trans-factors (compiling the splicing code)
Develop new method to modulate splicing (debugging the splicing code)

Paolo Tieri is a member of the ·Luigi Galvani· Interdept Center for Bioinformatics, Biophysics and Biocomplexity, Univeristy of Bologna, and postdoc research fellow at the Dept. of Experimental Pathology, University of Bologna, and at the BioPharmaNet research network of Emilia-Romagna region, Italy. He has completed his M.Sc. in Physics and received a Ph.D. in Systems Biology at University of Bologna. He is lecturer at the Biotechnology and Bioinformatics M.Sc. courses at University of Bologna, and member of the Linkgroup ( http://www.linkgroup.hu/) for network sciences.

Immunology and Ageing
Systems Biology
Systems Immunology
Network Biology
Computational Biology
Bioinformatics
Complex Systems
Self-organinzing Systems

Mobeen Raja is currently a research scientist in the field of Type-2 diabetes at Alberta Diabetes Institute, Edmonton-Alberta, Canada. He carried out his long-term postdoctoral fellowship in the field of potassium channels awarded by the Federation of European Biochemical Socities (FEBS) at Institute of Biophysics, Johannes Kepler University Linz, Austria. He received a prestigious Marie-Curie Intra-European Fellowship in 2006. He received his PhD in biophysical chemistry and molecular physiology from Max-Plank-Institute for Molecular Physiology, Dortmund, Germany, in 2002-2005. He is serving as an editorial board member of international journals and reviewer of 5 journals. Number of research publications and review articles: 16 Reviewer of EMBO Journal/Report, Nature Protocols, Biophysical Chemistry, Biochimie etc.

He is interested in membrane protein transporters (glucose transportes), Potassium ion channels and their roles in health and diseases. He has been involved in general and specific protein-protein, protein-ligand and protein-lipid interactions and molecular/homology modeling of functional domains.

Dr. Yogeshwer Shukla, Deputy Director and Head, Proteomics Laboratory Indian Institute of Toxicology Research(Formerly: Industrial Toxicology Research Centre)

ProteomicsCancer Chemopreventive Properties of Certain Dietary Constituents Evaluation of Mutagenic and Carcinogenic Potential of Agrochemicals

Taranjit Gujral is a Research Fellow Harvard Chemistry and Chemical Biology

Proteomics, Bioinformatics

Haibo Qiu is a Scientist at Regeneron Pharmaceuticals. He received his B.A. in 2001 at Jilin University, China and M.S. in 2004 in analytical chemistry at Changchun Institute of Applied Chemistry, Chinese Academy of Sciences. During the period of 2004-2009, he did his Ph.D. at University of California, Riverside, where he focused on the biological application of mass spectrometry in proteomics. Soon after, he joined Regeneron, a biopharmaceutical company in Tarrytown, New York, working on bioanalytical evaluation of newly developed monoclonal antibody drugs and mass spectrometry-based quantitative proteomics for biomarker identification and validation.

Mass spectrometry-based quantitative proteomics; Membrane proteomics; Protein therapeutic target and biomarker screening and validation; Bioanalytical characterization of therapeutic proteins and new method development; Post-translational modifications

Dr. Keshava Prasad is a Faculty Scientist in Institute of Bioinformatics, Bangalore. He obtained his Ph.D. degree in Mycology from Goa University, India. He is a recipient of Young Investigator Award from the Department of Biotechnology, Government of India, to investigate the role of protein tyrosine phosphatases in EGF signaling. He is also a Principal Investigator in a DBT-funded consortium to establish a national database for tuberculosis. He is leading IOB»s efforts on Human Protein Reference Database.In addition, he has a DBT-funded project to develop Mouse Protein Reference Database. Besides, he is also supported by a DBT grant for proteomic profiling of esophageal squamous cell carcinoma in collaboration with Kidwai Memorial Institute of Oncology, Bangalore. He is a reviewer for the journals Bioinformatics, DNA Research, International Journal of Molecular Sciences and Bioinformatics and Biology Insights. He is using differential proteomic strategies to profile the proteomes of infectious fungi including species of Candida and Aspergillus.

Proteomics, Proteogenomics and genome annotation, Quantitative proteomics and biomarkers, Bioinformatics and protein databases.

Ellis T. Benjamin maintain a Bachelor of Science degree (B.S) in Biology from the Richard Stockton College of New Jersey. This work centered on molecular biology focused on the isolation and cloning of Glucose-6-Phosphate Dehydorgenase (G6PDH) for enzymatic studies looking for metabolon formation. Additionally, I received a Masters of Science degree (M.S.) in Chemistry from Delaware State University focusing on crystal engineering. This work used predictable crystal packing motif to engineer non-linear optical properties (NLO) properties inside crystals. Finally, I received my Doctor of Philosophy degree (Ph.D.) in Bioenvironmental Science from Morgan State University My Ph.D. is in synthetic organic chemistry focusing on novel environmentally friendly microwave techniques for the synthesis of biologically active molecules. I have also had the pleasure to work as a MARC fellow at the Pittsburgh Supercomputing Center focusing on the modeling and interaction of several synthesized molecules with specific proteins. These experiment tried to elucidate specific results of ongoing biologically test for novel molecules. During my 15 years in the science field I have taken part in multiple research projects including those described here encompassing a wide variety of biological and chemical topics. This has given me a wide assortment of techniques and understandings about many regions of science. Some of these techniques are PCR, Cloning Techniques, GCMS, IR, NMR, and X-Ray Crystallography.

Synthesis and Application of novel materials against cancer and HIV
• Crystal Engineering
• Remediation of pollutants

David Lubman is currently the Maude T Lane Professor of Surgery at the University of Michigan Medical Center. He is also Professor of Pathology, Professor of Chemistry, an Associate Member of the Comprehensive Cancer Center and an Associate Member of the BioInformatics Program. He received his A.B. from Cornell University in 1975 and his Ph.D. in 1979 under the direction of Professor Richard N Zare at Stanford University in Physical Chemistry. He was a fellow at the Weizmann Institute in 1981 in the Department of Chemical Physics. He has been at the University of Michigan since 1983 initially in the Department of Chemistry where he developed a program in the areas of laser chemistry and mass spectrometry. His lab has published over 250 papers and graduated 56 Ph.D.s many of whom have gone on to hold leadership positions in the pharmaceutical and biotech industries. Most recently he has undergone a career switch and joined the Department of Surgery to develop a program in new technologies aimed at discovering markers of early cancer and prognosis of disease. Much of this work is focused in on glycoproteomic changes in proteins during cancer progression and newer work on mapping pathways in disease using a mass spec based approach. The group has filed numerous patents resulting in the development of new companies and new products involved in liquid mapping of proteins, protein microarrays, and new mass spec based technology and hardware. Dr Lubman is a Fellow of the American Association for the Advancement of Science and a member of the American Association of Cancer Research.

Biomarkers of Cancer, Glycoproteomics, Mass Spectrometry

Yurong Lai, Ph.D. Sr. Principal Scientist, Pfizer Global Research & Development, Groton Laboratories, Pfizer Inc.
Dr. Lai received his M.D from Fujian Medical University in China and his Ph.D. (Toxicology) from Sapporo Medical University in Japan in 1998. From 1998 to 2001, he was a research fellow of Japanese Society for Promotion (JSPS) in Department of Physiopathology, Graduate School of Medicine of Hokkaido University, followed by a position as Research Associate in Department of Pharmaceutics, University of Washington. In 2004, he moved to PDM, PGRD St. Louis and then Groton in 2010, Pfizer Inc. and has been serving as a PDM representative (PI) for preclinical project, postdoc supervisor and discipline leader for drug transporter. Research interests of Dr. Lai and his group include: 1) Discovery and development of drug candidates for the treatment of inflammation and pain. 2) Drug transporter related ADME/Tox, in particular hepatobiliary transporters. Current research projects involve absolute differences of hepatobiliary transporters across species, structure-activity relationship and the evaluation of in vitro/in vivo models to scale up human PK prediction. Dr. Lai is a patent inventor and the author of over 70 research papers/book chapters.

My research interests include:
1) hepatobiliary transport.
2) member protein proteomics.
3) Structure-Activities Relationship of transporters.
4) mechanism of drug absorption and disposition.
5) drug-drug interactions and regulation of ADMET protein expressions

The Myler laboratory played a key role in sequencing the "Tritryp" genomes, revealing that the protein-coding genes are arranged in long polycistronic gene clusters. Using genome-scale approaches such as microarray-based transcript mapping and chromatin immunoprecipitation (ChIP-chip), as well as more traditional molecular approaches such as electrophoretic mobility shifts assays, affinity chromatography, and in vitro transcription, we are now elucidating the molecular mechanisms involved in RNAPII-mediated transcription of protein-coding genes in L. major. In collaboration with Dan Zilberstein (at Technion, Israel), we are using genome-wide approaches (such as RNA-seq and tandem mass spectrometry), to identify and characterize changes in gene expression during differentiation from the insect form (promastigotes) to the mammalian form (amastigotes) of L. donovani and to elucidate the signaling pathways involved in this process. I am also PI of the NIAID-funded Seattle Structural Genomics Center for Infectious Disease (SSGCID), which includes investigators at Seattle BioMed, Emerald Biostructures, University of Washington and Pacific Northwest National Laboratories. To-date, we have solved over 250 three dimensional protein structures from NIAID Category A-C pathogens and organisms causing emerging or re-emerging infectious diseases. These protein structures serve as a blueprint for structure-based drug development, as well as facilitating vaccine development and other basic research.

Gene Expression, Cell Cycle & Chromosome Biology, Molecular Structure & Computational Biology

Dr.Rizwan Hasan Khan has received his Ph.D in Biotechnology from Aligarh Muslim University , India during the period of 1992-1996. Currently, he is working as  Associate Professor in the area of protein structure and function at Aligarh Muslim university. He has authored more than 120 research article/books. He is a member of SBC and ISCA, India. He has honoured as BOYSCAST Fellow and Commonwealth Fellow. The H index of Dr. Khan is 18.

My area of interest is Protein Folding / Stability  and albumin-drug interaction as well as purification/refolding of recombinant proteins

My research is mainly focused on understanding of the mechanism of activated transcription using quantitative mass spectrometry and mapping the protein-protein interactions in large protein complexes using chemical crosslinking and mass spectrometry. I have designed and synthesized new crosslinkers along with new programs and searching tools to facilitate the enrichment and characterization of crosslinked peptides using mass spectrometry and successfully applied these techniques in studying of protein architecture of pol II complex from partially immuno-purified samples.  I have involved in designing a new target quantitative mass spectrometry platform (iMSTIQ), which can trigger MS2 quantification independent of the ion intensity using LTQ-Orbitrap. I have also worked on the study of the mechanism of gene activation in yeast and identified a new gene GDS1 involving in the attenuation of SAGA and NuA4 transcription activation. I worked on a novel polymerase, pol IV, involving in siRNA mediated gene silence in plant for my PhD theses.

My research is mainly focused on understanding of the mechanism of activated transcription using quantitative mass spectrometry and mapping the protein-protein interactions in large protein complexes using chemical crosslinking and mass spectrometry.

I was graduated from DDU Gorakhpur University, India, with a specialization in microbial biotechnology. I was associated with Sam Higginbottom Institute of Agriculture, Technology and Science, Allahabad, India, as Assistant Professor (2007-2010) in the Department of Molecular and Cellular Engineering. Now I am working as Lecturer in the department of Biological Engineering, Inha University, South Korea. My functional area is to develop skin bioactive material by targeting various proteins of melanin biosynthesis pathways; and pathways associated antimicrobials discovery and design.

Skin Bioactive Materials; Bioinformatics; Microbial Biotechnology
 

I am currently a Senior Research Associate at the Lab for Personalized Medicine in Center for Biomedical Informatics, Beth Israel Deaconess Medical Center, Harvard Medical School. I participate in the development of cutting-edge software applications and suites for use in combating the complex challenges of biomedical science. I work on front-end web interface/web service development, back-end computational programming, tools development, and processing script. I was a Bioinformaticist in Washington University School of Medicine and Bioinformatics Intern in Monsanto Company.

Finding and testing WGA tools, Identifying the best-in-class tools, and maintaining a large and complex collection of these tools that are required for various LPM projects. Use an appropriate set of WGA tools to conduct a range of analyses on various types of genomic data and thus make a significant contribution to the success of LPM projects.

Dr. Suresh Mathivanan is a Laboratory Head in La Trobe University, Melbourne, Australia. After successfully completing a Masters degree in Biotechnology, a scholarship from the Department of Biotechnology allowed him to pursue an Advance Post Graduate Diploma in Bioinformatics at the Center for Excellence in Bioinformatics, Pondicherry University, India in 2004. He undertook a Ph.D. at the Johns Hopkins University, USA and Institute of Bioinformatics, India under the guidance of Dr. Akhilesh Pandey. During his doctoral studies, he worked on the integration of human proteomic and genomic data using distributed annotation system - named as the Human Proteinpedia. After gaining expertise in proteomics and bioinformatics, he joined Prof. Richard Simpson’s group as a postdoctoral researcher in 2008 at the Ludwig Institute for Cancer Research, Melbourne. He received a NH&MRC Biomedical Research Fellowship in 2011 to study exosomes secreted by colorectal cancer cells. He moved to the Department of Biochemistry at the La Trobe University to set up his own research group in 2011.

Colorectal cancer; Exosomes; Secretome; Bioinformatics; Microvesicles

Dr. Bhaskar Godugu has received his PhD in the field of Mass spectrometry at Indian Institute of Chemical Technology (IICT), India during the period of 2004 to 2007. After finishing his PhD, he was selected as a postdoctoral fellow at National Institute of Standards and Technology (NIST), USA and he worked for 3 years at NIST. Currently, he is working as a Research Assistant Professor in department of chemistry at University of Pittsburgh, USA. He has been successfully responding his Administrative responsibilities as a Director for the department Mass spec facility. Dr. Godugu has effectively applied his expertise in Mass spectrometry is one of the analytical method to characterize and identify the compounds from biological extracts and/or organic synthesis. He is serving as an editorial member of several reputed journals like Analytical & Bioanalytical Techniques, Analytical Chemistry Research and Journal of Mass spectrometry. He has authored twelve research articles in international peer reviewed journals. He is a member for the Science Advisory Board, Journal of American society for Mass spectrometry. 

Mass Spectrometry, Electron Ionization, Chemical Ionization, HPLC/MS platforms, peptide sequencing and posttranslational modification site determination with major emphasis on oxidation, methylation and deamidation, Extensive experience on data analysis by using NIST pipeline and MASCOT search

I Received my Ph.D in 2006 from University of Bayreuth.Presently working as Research Scientist at University of Pennsylvania, Philadelphia, USA

Structural biology and Biophysics

Ali Masoudi-Nejad received his Ph.D. in genomics from Kyoto University, Japan. He then did his first Post-Doc with Prof. Robbie Waugh at James Hutton Institute in Scotland and Prof. Paul H. Dear from MRC-LMB, Cambridge, UK. He returned to the Kyoto University and did two consecutive Post-Docs with Prof. Minoru Kanehisa, co-founder of GenBank and founder of KEGG (http://www.kanehisa.jp/en/kanehisa.html) in bioinformatics and systems biology. He then returned to Iran and founded the Laboratory of Systems Biology and Bioinformatics, LBB (http://LBB.ut.ac.ir) at University of Tehran. He is now associate professor of systems biology.

His main research interest focuses on computational systems biology, analysis of biological networks, network motif, RNAi pathway integration, cancer modeling, signaling pathway and genome-scale kinetic modeling.

Dr. Asad U Khan has received his PhD from Aligarh M University in collaboration with ICGEB, New Delhi during the period of 1998. Currently, he is working as Associate Professor in Aligarh M University. He has successfully completed his Administrative responsibilities as Editorial members of Scientific Domain of Global Science Book, Gene, Molecular & Cell Therapy, Medical & Pharma Board, Gene Genomes & Genomics, Biochemistry Processes Biotechnology & Molecular Biology. He /she is serving as an editorial member of several reputed journals like Bioinformation (Biomedical Information), Genomics proteomics and Bioinformatics (Elsevere), Asian Pacific Journal of Tropical Medicine (Elsevier), Journal of Mol. Genetic Medicine (Oxford), Journal of Industrial Research and Toxicology. He has authored over 100 research articles, 2 books. He is a member of (1) Life member of International Society of Genomics and Evolutionary Microbiology, (2) Life member of AMI (3) Member of New York Academy of Science. He has honoured as BOYSCAST Fellow of DST, Government of India to work as Visiting Scientist in one of the lab in University of Napoli, Italy in 2004. He is recipient of INSA Fellowship of 2005 for Indian lab. He is recipient of Young Scientist Award and Alembic Award of Association of Microbiologist of India in Medical Microbiology in 2006 and 2009 respectively. In year 2010 Dr. Khan has been given “Most Active Teachers Award of AMU” and DBT-CREST award of Department of Biotechnology.

Transcription biology and gene expression in multiple drug resistant genes in bacteria and Candia. Drug discovery against Dental caries.