alexa Nicolai Doliba | University of Pennsylvania
ISSN: 2167-0501

Biochemistry & Pharmacology: Open Access
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Nicolai Doliba

Nicolai Doliba Nicolai Doliba
Department of Biochemistry and Biophysics
University of Pennsylvania, USA

Nicolai Doliba is Assistant Professor of Biochemistry and Biophysics and Technical Director of Pancreatic Islet Cell Biology Core at Institute for Diabetes, Obesity and Metabolism, University of Pennsylvania, USA. His research has focused on the role of bioenergetics, ion transport and metabolic coupling factors in nutrient- and drug-stimulated insulin release at normal conditions and during diabetes mellitus. Using combinations of different methods and approaches, including 31P, 13C, and 1H Nuclear Magnetic Resonance Spectroscopy techniques, polarographic and phosphorescence methods of measuring O2 consumption, Ca2+ imaging and others, he attempts to directly address the essential mechanisms of stimulus-secretion coupling in pancreatic islets.

Research Interest

Role of bioenergetics, ion transport and metabolic coupling factors in nutrient- and drug-stimulated insulin release 


Bioenergetics and Type 2 Diabetes
Nicolai Doliba
Review Article: Biochem Pharmacol (Los Angel) 2017, 6:222
DOI: 10.4172/2167-0501.1000222
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