alexa Thomas Efferth | University of Mainz
ISSN: 2161-1009

Biochemistry & Analytical Biochemistry
Open Access

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Thomas Efferth

Thomas Efferth Thomas Efferth
Professor & Head
Department of Pharmaceutical Biology
University of Mainz
Germany
Biography

Professor Thomas Efferth is chair of the Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemsitry, University of Mainz, Mainz, Germany.  He is biologist by training and obtained his degree from the Technical University of Darmstadt, Germany. His doctoral thesis was completed at the German Cancer Research Center, Heidelberg, Germany, in 1990. Dr. Efferth was awarded the Ludolf-Krehl-Prize of the Southwest German Association for Medicine in 1991 and the Willmar-Schwabe-Award of the German Society for Medicinal Plant Research in 2006. From 2005-2009 he headed a research group for Pharmaceutical Biology at the German Cancer Research Center, Heidelberg, Germany. From 2007-2009 he was associate professor  at the University of Heidelberg. In 2009, he took over the Chair of Pharmaceutical Biology  at the University of Mainz. Furthermore, he is honorary professor at the Northeast Forestry University, Harbin, China and visiting professor at the Zhejiang Chinese Medical University, Hangzhou, China. Thomas Efferth has published over 200 original papers and over 80 reviews in peer-reviewed journals in the field of cancer research, pharmacology, and pharmacogenomics and natural products. He holds four patents. The scientific results were communicated in over 120 oral presentation and invited lectures and over 100 poster presentations at national and international conferences and meetings. A textbook on Molecular Pharmacology and Toxicology written by him appeared in 2006. He is co-editor and editorial board member of 13 scientific journals and scientific advisory board member of several institutions.

Research Interest

The focus of Dr Efferths research is on tumor pharmacology and the development of novel options for treatment and diagnosis of cancer. A major topic is research on natural products derived from medicinal plants. Two fields are in the center of his interest
1. Molecular pharmacology and toxicology of natural products. Drug resistance and severe side effects represent major obstacles of current chemotherapy. This necessitates the identification of novel compounds from plants with anticancer activity. The aims are a. the identification of novel drugs with improved tumor specificity and efficacy against drug-resistant tumors as well as less adverse side effects and b.  the analysis of underlying molecular modes of action in tumor cells and normal tissues. A current research project focuses on chemically pure compounds derived from medicinal plants and their analysis by systems biology

2. Genome-wide expression profiling and genomic aberrations in tumors. Drug resistance of tumor cells reduces the probability for patients to be cured and reduce survival. The knowledge of determinants which affect drug responsiveness of tumors and prognosis of patients would allow the design tailor-made treatment protocols for each individual patient. The aim is to develop techniques for the predictive determination for individualized therapy options and the implementation of natural products for treatment. The overall aim is the integration of active principles of traditional Chinese medicine into western medicine.
 

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Publications

Phytochemical Screening of Medicinal Plants of the Kakamega Country, Kenya Commonly Used against Cancer
Dominic O Ochwang’I, Charles N Kimwele, Jemimah A Oduma, Peter K Gathumbi, Stephen G Kiama and Thomas Efferth
Research Article: Med Aromat Plants 2016, 5: 277
DOI: 10.4172/2167-0412.1000277
 
Ayurveda for Cancer Treatment
Paramasivan Poornima and Thomas Efferth
Editorial: Med Aromat Plants 2016, 5: e178
 
Editors Note on Techniques to Isolate and Characterize Bio Active Compounds
Thomas Efferth
Editorial: Med Aromat Plants 2016, 5: E176
DOI: 10.4172/2167-0412.1000e176
 
Doctrine of Signatures Mystic Heritage or Outdated Relict from MiddleAged Phytotherapy?
Thomas Efferth and Henry J Greten
Editorial: Med Aromat Plants 2016, 5: E177
DOI: 10.4172/2167-0412.1000e177
 
Traditional Medicine with Plants – Present and Past
Thomas Efferth and Henry Johannes Greten
Editorial: Med Aromat Plants 2014, 3:3
DOI: 10.4172/2167-0412.1000e151
 
Targeting Angiogenesis By Phytochemicals
Onat Kadioglu, Ean Jeong Seo and Thomas Efferth
Review Article: Med Aromat Plants 2012, 2: 134
DOI: 10.4172/2167-0412.1000134
 
Autophagy by Natural Products in Cancer Cells
Thomas Efferth
Editorial: Biochem Anal Biochem 2012, 1: e128
DOI: 10.4172/2161-1009.1000e128
 
Quality Control for Medicinal Plants
Thomas Efferth and Henry Johannes Greten
Editorial: Med Aromat Plants 2012, 1:e131
DOI: doi:10.4172/2167-0412.1000e131
 
Medicinal and Aromatic Plant Research in the 21st Century
Thomas Efferth and Henry Johannes Greten
Editorial: Medicinal Aromatic Plants 2012, 1: e110
DOI: 10.4172/2167-0412.1000e110
 
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