alexa Electrically Controlled Release Of Ibuprofen From Pectin Hydrogel In Transdermal Drug Delivery
ISSN: 2150-3494

Chemical Sciences Journal
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading Please wait..

4th European Chemistry Congress
May 11-13, 2017 Barcelona, Spain

Sirivipa Mongkolkitikul and Anuvat Sirivat
Chulalongkorn University, Thailand
Posters & Accepted Abstracts: Chem Sci J
DOI: 10.4172/2150-3494-C1-009
Transdermal drug delivery system (TDDS) is the alternative route to transport drug molecule to a systematic circulation through the human skin. The major advantage of TDDS is the ability to avoid the first-pass metabolism. However, TDDS has certain limitations: the level of drug permeated across the skin is low and the drug size has an adverse effect on the permeation. To improve those limitations, the electrical potential and conductive polymer were utilized. This work attempted to design a transdermal patch consisting of ibuprofen as a model drug and pectin hydrogel as a drug matrix. The effects of the crosslinking agent type, crosslinking ratio (the mole of the crosslinking agent to the mole of the pectin monomer), mesh size, and electric potential were investigated. The diffusion coefficients and the release mechanism of the ibuprofen on the pectin hydrogels were determined and investigated using a modified Franz-Diffusion cell in an MES buffer solution of pH 5.5, at a temperature of 37 ยบC, for 48 h. The amount of drug release was analyzed by UV-Visible spectrophotometry. The result showed the drug diffusion coefficient increased with increasing mesh size and electric potential.

Sirivipa Mongkolkitikul completed her B. Eng. with a second-class honour in Petrochemical and Polymeric Materials from Silpakorn University, Thailand in 2014, and now she is studying for a Master degree in Polymer Science at the Petroleum and Petrochemical College, Chulalongkorn University, Thailand.

Email: [email protected]

image PDF   |   image HTML

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

gen[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version