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Background: Psoriasis is an autoimmune disease that inflicts a pronounced negative impact on patients???
quality of life. A mixed-method study was designed aimed to provide a multi perspective understanding of
the burden of disease to determine relative concerns or patients and physicians and to determine outcome
measures and develop qualitative interviews.
Methods: A Group Concept Mapping (GCM) exercise was performed in which participating patients and
clinicians responded to an online prompt asking what qualities they want in an ideal treatment for psoriasis.
Responses were sorted into groups and rated according to importance by participants, mapped into domains
and statistically analyzed for correlation between clinician and patient responses.
Results: Twenty (20) patients and 10 clinicians participated in the study. Using multidimensional scaling and
cluster analysis, seven domains for treatment importance were configured. The order of importance of the
domains based on their average ratings showed that concepts are located along the slope intercept, indicating
there was a strong correlation between the two participant groups. Both groups identified accessibility, safety,
general efficacy and proximal benefits as the most important domains. All domains per combined ratings were
regarded as at least moderately important because they had an average treatment importance value above the
midpoint on the 0 to 10 rating scale (>5.0). Good agreement was found across individual concept ratings as
Conclusion: This GCM study found that patients and clinicians were generally in agreement over which
factors are most important in the treatment of psoriasis.
Colby C Evans is the Research Committee Chair and the Immediate Past Chair of the Board of Directors for the National Psoriasis Foundation. He has completed his Medical degree and Residency in Dermatology at the University of Texas Southwestern Medical Center in Dallas, followed by a Clinical Fellowship at the St. John’s Institute of Dermatology in London, England. He has pursued his Under-graduation degree from Wesleyan University.
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