alexa Probabilistic Ecotoxicological Risk Assessment Of Ionic Liquids
ISSN: 2161-0495

Journal of Clinical Toxicology
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9th Euro-Global Summit on Toxicology and Applied Pharmacology
June 22-24, 2017 Paris, France

Dzulkarnain Zaini, Muhammad Ishaq Khan, Azmi B Mohd Shariff and Muhammad Moniruzzaman
UTP, Malaysia
Posters & Accepted Abstracts: J Clin Toxicol
DOI: 10.4172/2161-0495-C1-025
Abstract
Current ecotoxicological information on ionic liquids (ILs) is limited because of unavailability of exposure data which is one of the major issues in the assessment of ecotoxicological risks of ILs. Conventionally, only hazard assessment of ILs is practiced by conducting toxicity tests. There is a need to figure out some statistical techniques to obtain safe environmental concentrations of ILs. In current research, probabilistic ecotoxicological risk assessment was conducted using chemical species sensitivity distributions (CTDs) and chemical toxicity distributions (SSDs). Probabilistic ecotoxicological risk assessment (PETRA) method was adopted due to unavailability of exposure data and thus, effect data was used from acute toxicity literature. Subsequently, experimental toxicity data of ILs for different species from literature was also used. SSD method was applied to estimate guideline values and confidence limits for selected ILs. Meanwhile, toxicity distributions were calculated for each of the species to obtain the 1st and 5th percentiles, to provide an estimate of the probability of finding ILs that will be hazardous to bacteria at or below a given concentration (screening point values). Screening-predicted no-effect concentrations (sPNECs) were calculated from SPVs. In current work 95% of L. monocytogenes has been protected at a concentration of 3.55 mmol/L of studied ILs. This methodology is useful in the assessment of the potential risks of ILs where exposure data is not available. Thus, it has been concluded that the application of CTDs improved the assessment when a group of ILs with same toxic behavior exposed to single species of the ecosystem. Meanwhile, it also has been observed that the guideline values (GVs) from SSD of each single ionic liquid are showing its effect on the range of species. Moreover, this methodology will enhance the safety of environment containing different species.
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