Embelin has been isolated from the dry ripe berries of Embelin ribes, which are widely used as traditional medicine in
India, The berries of Embelin ribes are reported to contain mainly benzoquinone derivatives it is 2, 5-dihydroxy, 6-undecyl
benzoquinone, Embelin reported to have many microbial activities like anti -inflammatory, antibacterial, antitumor, antioxidant,
the compound itself has been used in India for long time in the treatment of several diseases.
In the present investigation Embelin undergoes cyclisation with guanidine hydrochloride to give a compound with imidazole
ring. Imidazole provides one of the most fascinating classes of compounds recognized for various biological and pharmacological
activities. Imidazole units are also used as synthetic intermediates, chiral auxiliaries, chiral catalysis and ligands for asymmetric
catalysis.in various synthetic pharmaceuticals. We synthesized 2-amino-6-hydroxy-4-undecyl-5H-benzo(d)imidazole-5-
one(fig.1) is more biologically significant compound, than the above mentioned Embelin and Imidazole.
G.Brahmeshwari has completed her Ph.D in 1995 from Kakatiya University; Warangal (A.P) India .She has 20 + years academic experience in
teaching at various institutions. Currently she is working as Assistant professor of Chemistry in Arts and Science College, Kakatiya University, and
she served as Joint Director of Padmakshi Women?s Hostel K.U, and In-charge Dept. of Chemistry in Arts & Science College Kakatiya University, and
also organized Workshop for UG Courses on revised syllabus. She is acting Deputy Director of Science Courses SDLCE and she is the member of
Board of Studies for UG. Also she has been in the research field by admitting five Research scholars under her supervision since November 2011.
She has published 9 papers in reputed journals
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals